THE LONGEVITY EQUATION JOURNAL

The Longevity Equation Journal

A physician-led exploration of the biological systems that shape aging, performance, and long-term resilience — grounded in clinical practice and thoughtful analysis.

Anil Bajnath, MD · Institute for Human Optimization
Physician-Led Precision & Longevity Medicine
New entries published periodically. Explore by topic below.

Longevity equation journal

The Oxygen–Mitochondria Axis: Why Energy, Aging, and Disease Share the Same Bottleneck

The Oxygen–Mitochondria Axis: Why Energy, Aging, and Disease Share the Same Bottleneck

Institute for Human Optimization Team
Published on: 20/12/2025

Explore how the oxygen–mitochondria axis is the hidden bottleneck behind low energy, chronic disease, and aging. Discover why mitochondria—not just calories—determine performance, healthspan, and metabolic flexibility. Learn how VO₂ max, IHHT, and precision testing at IFHO train and optimize this critical system at the cellular level for true longevity.

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